Chiefs vs. Bills odds, picks, line, how to watch, live stream: Model reveals 2022 Week 6 NFL predictions

The most anticipated game on the Week 6 NFL schedule will take place at Arrowhead Stadium on Sunday afternoon when the Kansas City Chiefs host the Buffalo Bills in an AFC showdown. Kansas City and Buffalo traded the lead three times and scored 25 points in the final two minutes of regulation in last year’s playoff matchup, as the Chiefs eventually escaped with the win. The Bills lead the NFL in passing offense this season, but the Chiefs lead the league in scoring offense. You can stream the game on Paramount+, which you can try for free for 30 days with the promo code NFLONCBS.

Kickoff for Sunday’s game from Arrowhead Stadium in Kansas City is set for 4:25 p.m. ET. Buffalo is a 2.5-point favorite in the latest Chiefs vs. Bills odds from Caesars Sportsbook, and the over/under for total points is 54.5. Sunday’s matchup can be seen live on CBS and streamed live on Paramount+ with their must-have Premium plan, which you can try free for 30 days with the promo code NFLONCBS.

Paramount+ now has levels of membership so you can watch your local NFL on CBS matchups and much more. The Premium Plan is $9.99 per month and you can watch your local CBS live stream, including plenty of sports like SEC on CBS, NFL on CBS, and the PGA Tour, with no ads, on demand and the ability to download episodes for offline viewing. Before the end of October, you can try Paramount+ for free for 30 days with the promo code NFLONCBS, so sign up now here.

How to watch Chiefs vs. Bills 

• Chiefs vs. Bills date: Sunday, Oct. 16
• Chiefs vs. Bills time: 4:25 p.m. ET
• Chiefs vs. Bills TV channel: CBS 
• Chiefs vs. Bills streaming: Paramount+ (use code NFLONCBS for 30 days free)

Week 6 NFL picks for Bills vs. Chiefs

Before tuning into Sunday’s Chiefs vs. Bills game, you need to see the NFL picks from SportsLine’s advanced computer model. The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 6 of the 2022 NFL season on an incredible 146-106 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

For Bills vs. Chiefs, the model is picking Buffalo (-2.5) to cover the spread. This will be the fifth time these two teams have played in the last two calendar years and the Chiefs have won three out of the previous four matchups. However, it appears as if Buffalo has taken it up a notch in 2022 and even though the Eagles are the only unbeaten team remaining, the Bills have been the most statistically dominant team in the league.

Sean McDermott’s squad ranks second in the NFL in scoring offense (30.4 points per game) and first in scoring defense (12.2 ppg) and they’re top two in the league in total offense and defense as well. The Bills also rank first in the NFL in team DVOA (38.7%) and if Buffalo is going to establish itself as the best team in the NFL, getting over the Kansas City hurdle is a must.

Meanwhile, the Chiefs have some serious issues defensively, having allowed 375 yards of total offense or more in three of the last four games. Kansas City ranks 24th in the NFL in scoring defense (25.0 ppg) and 19th in pass DVOA. With Allen out to make a point, the model predicts that he piles up well over 300 yards of total offense to help the Bills cover the spread in more than 50% of simulations. You may be able to stream the game here.

How to watch, live stream the NFL on CBS

Now that you know what to pick, get ready to watch your live local NFL on CBS games on Paramount+ on any device you want. Before the end of October, you can try out Paramount+ for free with the promo code NFLONCBS. Visit Paramount+ now to stream your live local CBS sporting events, including the NFL, SEC on CBS, and so much more.